… by activating endogenous opioid-dependent pathways [12]. … some of the opiorphin analogs’
antinociceptive effects we … ; opiorphin-loaded Alg-beads coated with weak natural cross-…

… Human opiorphin, a natural antinociceptive modulator of opioid-dependent pathways. Proc
… The antidepressant-like effect of human opiorphin via opioiddependent pathways in mice. …

… Here, we investigated the effect of natural enkephalinase inhibitor human opiorphin (HO) on
… colitis by inhibiting TLR4/NF-κB pathway activation and improving intestinal barrier function …

… and anxiolytic properties in humans and rodents. Given the fact … For instance, opiorphin,
which is an inhibitor of endogenous … receptor-BDNF signalling pathway in the dPAG accounts for …

… stimulation and exert a potent antinociceptive effect. However, the … endogenous opioid-dependent
transmission, opiorphin … Opiorphin is a naturally occurring human peptide that protects …

… Human opiorphin is an endogenous pentapeptide with modulatory capabilities of opioid
signaling pathways. It … This suggests that opiorphin may play a role in the modulation of orofacial …

… to the extraction of opiorphin in human saliva prior to its quantification by LC-MS/MS.
Opiorphin, a pentapeptide first isolated in 2006 from human saliva, is a natural enkephalin with a …

… - and heterodimers of natural enkephalinase inhibitors (opiorphin; sialorphin; spinorphin) …
in the antinociception [5], the regulation of gastrointestinal motility [5], the modulation of the …

… Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways. Proc
… Identi cation of human opiorphin, a natural antinociceptive modulator of opioiddependent …

… and potentiates intrinsic signaling pathways, which would … allosteric modulator of µ-opioid
receptor, on antinociception by … (MERF IC 50 in the presence of opiorphin was 5.8 nM; IC 50 in …